Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661227 | 0.87 | MEN1 (0.42) | HSD17B10POLBKDM4EHPGDALDH1A1 | |
| SCHEMBL12859084 | 0.85 | HSD17B10 (0.53) | HSD17B10POLBKDM4EHPGDTSHR | |
| SCHEMBL4662697 | 0.84 | NAMPT (0.42) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL4661432 | 0.84 | NAMPT (0.42) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL14686239 | 0.82 | HSD17B10 (0.50) | HSD17B10POLBKDM4EHPGDTSHR | |
| SCHEMBL3766986 | 0.81 | SMN1; SMN2 (0.42) | HSD17B10POLBHPGDIDO1ALDH1A1 | |
| SCHEMBL6953610 | 0.81 | HSD17B10 (0.49) | HSD17B10POLBKDM4EHPGDTSHR | |
| SCHEMBL28864994 | 0.81 | HSD17B10 (0.49) | HSD17B10POLBKDM4EHPGDTSHR | |
| SCHEMBL11152408 | 0.79 | IDO1 (0.43) | POLBKDM4ETSHRIDO1KMT2A | |
| SCHEMBL28745521 | 0.78 | KDM4E (0.54) | HSD17B10POLBKDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1216963-A | — | — | None | — | — | JP | disclosed |
| JP-H01216963-A | PRODUCTION OF OPTICALLY ACTIVE AMINOALCOHOL | FUJI YAKUHIN KOGYO KK | 1989-08-30 | — | — | JP | disclosed |