Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28865360

C1CCOC1.OB(O)c1cncnc1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9139 0.82
Water SCHEMBL1662662 0.79 HCAR2 (0.36)
Water SCHEMBL2326354 0.79 HCAR2 (0.36)
Tetrahydrofuran SCHEMBL28247226 0.76 ENPP2 (0.41)
Tetrahydrofuran SCHEMBL8433132 0.71 ALDH1A1 (0.57) ALDH1A1
Phenylboronic Acid SCHEMBL30296306 0.70 ENPP2 (0.64) ALDH1A1
SCHEMBL128201 0.67 ENPP2 (0.62)
SCHEMBL28967087 0.66 ENPP2 (0.36) ALDH1A1
Tetrahydrofuran SCHEMBL8029807 0.65
Pyrimidine SCHEMBL27840500 0.64 ALDH1A1 (0.47) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108690052-A 5- aryl -1- imino group -1- oxos-[1,2,4]Thiadiazine 豪夫迈·罗氏有限公司 2018-10-23 CN disclosed