Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929659 | 0.83 | ALDH1A1 (0.46) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL16416212 | 0.83 | POLB (0.42) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL12303023 | 0.82 | POLB (0.58) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL11932382 | 0.80 | POLB (0.67) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL20542377 | 0.80 | POLB (0.56) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL24997068 | 0.80 | POLB (0.52) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL8341632 | 0.80 | POLB (0.52) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL28242652 | 0.80 | — | — | |
| SCHEMBL16415410 | 0.79 | L3MBTL1 (0.40) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL3872020 | 0.79 | ALDH1A1 (0.51) | POLBTSHRLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693193-B | Aryl methoxy isoindoline derivative and composition and their application method including it | 细胞基因公司 | 2018-09-18 | — | — | CN | disclosed |