Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751273 | 0.83 | ELANE (0.41) | ELANEMAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL7180695 | 0.83 | ELANE (0.41) | ELANEMAPTRECQLHSD17B10ALDH1A1 | |
| SCHEMBL2048211 | 0.81 | ELANE (0.40) | ELANEMAPTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL2810165 | 0.80 | ELANE (0.39) | ELANEMAPTRECQLHSD17B10ALDH1A1 | |
| SCHEMBL27633096 | 0.80 | ZDHHC2 (0.45) | ELANERECQLPPARGKMT2A | |
| SCHEMBL3184463 | 0.80 | MTNR1A (0.47) | MAPTRECQLALDH1A1 | |
| SCHEMBL432377 | 0.79 | ELANE (0.42) | ELANEMAPTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL4057744 | 0.79 | ELANE (0.42) | ELANEMAPTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL20542045 | 0.79 | ELANE (0.38) | ELANEMAPTRECQLALDH1A1BTN3A1 | |
| SCHEMBL27598507 | 0.79 | ZDHHC2 (0.47) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104582694-B | Dihydroorotic acid dehydrogenase inhibitor | 线粒体科学公司研究所 | 2018-10-02 | — | — | CN | disclosed |