Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.30 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.30 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.30 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28249806 | 0.84 | OPRM1 (0.35) | OPRM1PTGER4PTGER2PTGDRCYP2C19 | |
| SCHEMBL28250543 | 0.80 | CYP4F2 (0.34) | OPRM1PTGER4PTGER2PTGDRCYP2C19 | |
| SCHEMBL16453921 | 0.77 | CYP4F2 (0.34) | OPRM1PTGER4PTGER2PTGDRKMT2A | |
| SCHEMBL7055664 | 0.73 | CYP2C19 (0.37) | CYP2C19AGTR2 | |
| SCHEMBL746366 | 0.73 | CYP2C19 (0.31) | PTGER4PTGER2PTGDRCYP2C19AGTR2 | |
| SCHEMBL5186884 | 0.72 | TET3 (0.33) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL28501410 | 0.72 | PTGER2 (0.40) | PTGER4PTGER2PTGDRKMT2ACYP2C19 | |
| SCHEMBL2037209 | 0.72 | CYP2C19 (0.33) | OPRM1TET3KMT2AFBXL19CXXC5 | |
| SCHEMBL28112880 | 0.70 | CYP2C19 (0.37) | KMT2ACYP2C19 | |
| SCHEMBL20608126 | 0.68 | CYP4F2 (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602823-A | As deubiquitinating enzymes（DUB）The spiral shell of inhibitor-condensation pyrrolidin derivatives | 特殊治疗有限公司 | 2018-09-28 | — | — | CN | disclosed |