P-Xylene

P-Xylene

SCHEMBL28865890

Cc1ccc(C)cc1.N=O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.73
TDP1 Q9NUW8 2/20 0.73
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
CYP2A6 P11509 1/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TSHR P16473 2/20 0.47
ALOX12 P18054 1/20 0.47
POLB P06746 1/20 0.46
HSD17B10 Q99714 1/20 0.45
F2 P00734 1/20 0.45
ELANE P08246 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL11772917 0.85 ACHE (1.00) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL460348 0.85 ACHE (1.00) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL11770184 0.85 ACHE (1.00) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL771 0.85
P-Xylene SCHEMBL29262417 0.82 ACHE (0.73) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL26852 0.82 ACHE (0.73) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL28448852 0.82 ACHE (0.73) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL27663473 0.82 ACHE (0.73) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL28884038 0.82 ACHE (0.73) ACHETDP1ALDH1A1LMNACA1
P-Xylene SCHEMBL28248564 0.82 ACHE (0.73) ACHETDP1ALDH1A1LMNACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108778244-A DELIVERY OF DRUG NANOPARTICLES AND METHODS OF USE THEREOF DFB索里亚有限责任公司 2018-11-09 CN disclosed