Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.38 |
| ▸ | ABL1 | P00519 | 6/20 | 0.38 |
| ▸ | LYN | P07948 | 4/20 | 0.38 |
| ▸ | BCR | P11274 | 3/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | ARAF | P10398 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.38 |
| ▸ | CSK | P41240 | 1/20 | 0.38 |
| ▸ | ABL2 | P42684 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676637 | 0.83 | BTK (0.56) | AAK1DDR1BTK | |
| SCHEMBL16794451 | 0.83 | BTK (0.56) | AAK1DDR1BTK | |
| SCHEMBL28238068 | 0.82 | BTK (0.45) | AAK1ACHEABL1LYNBCR | |
| SCHEMBL29676609 | 0.75 | BTK (0.48) | DDR1ABL1LYNBCRRIPK2 | |
| SCHEMBL28238065 | 0.74 | NR1H2 (0.42) | DDR1 | |
| SCHEMBL28257788 | 0.73 | AAK1 (0.41) | AAK1BTK | |
| SCHEMBL16793886 | 0.72 | BTK (0.66) | AAK1BTK | |
| SCHEMBL16794371 | 0.71 | AAK1 (0.62) | AAK1BTK | |
| SCHEMBL16814190 | 0.70 | BTK (0.69) | AAK1BTK | |
| SCHEMBL16794185 | 0.68 | BTK (0.44) | AAK1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-108947913-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-07 | — | — | CN | disclosed |