Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 15/20 | 0.40 |
| ▸ | GPR183 | P32249 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24192812 | 0.80 | NR1H2 (0.47) | NR1H2DDR1GPR183 | |
| SCHEMBL16793983 | 0.78 | BTK (0.49) | DDR1EPHX2 | |
| SCHEMBL28126278 | 0.76 | NR1H2 (0.40) | NR1H2DDR1GPR183 | |
| SCHEMBL28866491 | 0.74 | AAK1 (0.40) | DDR1 | |
| SCHEMBL2800197 | 0.73 | PDE3B (0.55) | NR1H2GPR183 | |
| SCHEMBL18580987 | 0.73 | GPR183 (0.48) | NR1H2DDR1GPR183 | |
| SCHEMBL23124595 | 0.71 | KDM1A (0.43) | EPHX2 | |
| SCHEMBL13260737 | 0.70 | NR1H2 (0.45) | NR1H2DDR1 | |
| SCHEMBL18908934 | 0.69 | DDR1 (0.47) | NR1H2DDR1GPR183 | |
| SCHEMBL22624006 | 0.69 | ACHE (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-108947913-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-106459002-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2018-08-21 | — | — | CN | disclosed |