SCHEMBL28866511

SCHEMBL28866511

CCCCC(Cl)(C(=O)c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES1 P23141 7/20 0.44
CES2 O00748 6/20 0.44
NAAA Q02083 1/20 0.38
HSP90AA1 P07900 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28458216 0.80 CES1 (0.41) CES1CES2ALDH1A1MAPTHPGD
SCHEMBL1671010 0.78 NAAA (0.47) CES1CES2NAAAALDH1A1MAPT
SCHEMBL10704887 0.77 ALDH1A1 (0.35) CES1CES2ALDH1A1
SCHEMBL10516214 0.75 CES1 (0.43) CES1CES2NAAAALDH1A1MAPT
SCHEMBL28163593 0.74 CES1 (0.50) CES1CES2NAAAALDH1A1LMNA
SCHEMBL27317630 0.74 CES1 (0.44) CES1CES2NAAAALDH1A1MAPT
SCHEMBL15261109 0.73 CES1 (0.49) CES1CES2NAAAALDH1A1LMNA
SCHEMBL5321540 0.73 CES1 (0.49) CES1CES2NAAAALDH1A1LMNA
SCHEMBL6932937 0.73 GAA (0.50) CES1CES2NAAAALDH1A1MAPT
SCHEMBL26064181 0.73 CES1 (0.49) CES1CES2NAAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109053482-A A kind of preparation method of N- (4- aminobenzoyl)-Pidolidone 上海雅本化学有限公司 2018-12-21 CN disclosed