Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375765 | 0.85 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2PARP10CYP1A2 | |
| Methyl Alcohol SCHEMBL3396777 | 0.83 | ALDH1A1 (0.53) | RAB9ANPC1SMN1; SMN2PARP10CYP1A2 | |
| SCHEMBL14640301 | 0.82 | HRH1 (0.52) | SMN1; SMN2PARP10CYP1A2ALDH1A1TSHR | |
| SCHEMBL78000 | 0.81 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6013805 | 0.81 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2PARP10CYP1A2 | |
| SCHEMBL29390571 | 0.81 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7500894 | 0.80 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| Water SCHEMBL7798110 | 0.80 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL15662173 | 0.79 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2PARP10CYP1A2 | |
| SCHEMBL11561793 | 0.79 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2PARP10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069481-A | Methods and compounds for restoring function of mutant p53 | 皮姆维制药公司 | 2018-12-21 | — | — | CN | disclosed |