Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906697 | 0.80 | ALDH1A1 (0.50) | MAPTPAK1ADRA1DADRA1AADRA1B | |
| SCHEMBL8437508 | 0.77 | ALDH1A1 (0.49) | MAPTADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL13369342 | 0.77 | MAPT (0.44) | MAPTPAK1ADRA1DADRA1AADRA1B | |
| SCHEMBL5739853 | 0.73 | ALDH1A1 (0.58) | MAPTALDH1A1SMN1; SMN2TDP1LMNA | |
| SCHEMBL4565387 | 0.70 | SMN1; SMN2 (0.46) | MAPTALDH1A1SMN1; SMN2TDP1LMNA | |
| SCHEMBL6676186 | 0.69 | ESR1 (0.47) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8436491 | 0.68 | GPR119 (0.49) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10237127 | 0.68 | ALDH1A1 (0.41) | MAPTALDH1A1SMN1; SMN2TDP1LMNA | |
| SCHEMBL3124970 | 0.68 | AR (0.40) | ALDH1A1LMNAKDM4E | |
| SCHEMBL5748476 | 0.68 | ALDH1A1 (0.62) | MAPTMAOAALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |