Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756372 | 0.81 | GBA1 (0.43) | TSHRKDM4EALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL13322100 | 0.74 | CYP2C19 (0.47) | TSHRKDM4EALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL7207372 | 0.72 | CRHBP (0.54) | TSHRSMN1; SMN2CYP2C19CRHBPCRHR2 | |
| SCHEMBL29892730 | 0.72 | CRHBP (0.54) | TSHRSMN1; SMN2CYP2C19CRHBPCRHR2 | |
| SCHEMBL11296484 | 0.72 | SIGMAR1 (0.49) | — | |
| SCHEMBL5065124 | 0.70 | KDM1A (0.52) | TSHRSMN1; SMN2MAOAMAOB | |
| SCHEMBL31623051 | 0.70 | CYP2C19 (0.40) | TSHRKDM4EALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL18030723 | 0.70 | CARM1 (0.47) | TSHRSMN1; SMN2CARM1PRMT6PRMT8 | |
| SCHEMBL13338024 | 0.69 | CYP19A1 (0.44) | TSHRKDM4EALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL1498777 | 0.68 | CYP2C19 (0.64) | TSHRKDM4EALDH1A1SMN1; SMN2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723347-B2 | Substituted phenylamino-pyrimidines | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20080269268-A1 | Substituted Phenylamino-Pyrimidines | BAYER HEALTHCARE AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269268-A1 | Substituted Phenylamino-Pyrimidines | TYMP, DPYD, HPRT1 | TSHR 3693/4885KDM4E 2250/4885ALDH1A1 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.