SCHEMBL288669

SCHEMBL288669

COc1cc(O)ccc1CO

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.57
PDCD1 Q15116 1/20 0.51
CD274 Q9NZQ7 1/20 0.51
PDE4A P27815 1/20 0.50
PDE4B Q07343 1/20 0.50
PDE4C Q08493 1/20 0.50
PDE4D Q08499 1/20 0.50
MAPT P10636 2/20 0.45
CYP3A4 P08684 1/20 0.45
APP P05067 1/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
ELANE P08246 1/20 0.43
CTSG P08311 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415192 1.00 MAOB (0.57) MAOBPDCD1CD274PDE4APDE4B
Vanillyl Alcohol SCHEMBL10533321 0.85 MAOB (0.61) MAOBCYP3A4GAATSHRMAPK1
SCHEMBL6297020 0.85 MAOB (0.59) MAOBMAPTCYP3A4APPESR1
SCHEMBL9862162 0.84 MAOB (0.53) MAOBMAPTCYP3A4APPESR1
SCHEMBL4847162 0.83 MAOB (0.52) MAOBPDE4APDE4BPDE4CPDE4D
SCHEMBL8296534 0.83 MAOB (0.57) MAOBMAPTCYP3A4APPESR1
SCHEMBL13318421 0.83 MAOB (0.57) MAOBMAPTCYP3A4APPESR1
SCHEMBL23671876 0.82 MAOB (0.55) MAOBMAPTCYP3A4APPESR1
SCHEMBL772479 0.82 MAOB (0.55) MAOBMAPTCYP3A4APPESR1
SCHEMBL5216474 0.82 MAOB (0.55) MAOBMAPTCYP3A4APPESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341503-B1 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-02-13 EP claimed
US-6835212-B2 Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme WELLA AKTIENGESELLSCHAFT (DE) 2004-12-28 US claimed
EP-1341503-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2003-09-10 EP claimed
US-20030041391-A1 Agent and method for dyeing keratin fibres Wella GmbH (DE) 2003-03-06 US claimed
WO-2002047633-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-06-20 WO claimed
US-5726243-A Mild solid-phase synthesis of aligned, branched triple-helical peptides REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1998-03-10 US claimed
US-5576419-A Mild solid-phase synthesis of aligned branched triple-helical peptides REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1996-11-19 US claimed
EP-0292729-B1 PROCESS FOR SOLID PHASE PEPTIDE SYNTHESIS BACHEM AG (CH) 1992-04-22 EP claimed
EP-0292729-A2 Process for solid phase peptide synthesis BACHEM AG (CH) 1988-11-30 EP claimed
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2026-04-16 US disclosed
CN-119032076-A Novel compounds and uses thereof 株式会社安提昂 2024-11-26 CN disclosed
EP-4345104-B1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-08-28 EP disclosed
CN-118043339-A Antimicrobial peptidomimetics 巴斯利尔药物阿尔施维尔国际股份公司 2024-05-14 CN disclosed
WO-2024068827-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-04-04 WO disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
US-4914151-A Resin-linker combination for the solid-phase synthesis of peptides and intermediates BACHEM FEINCHEMIKALEIN A.G. (CH) 1990-04-03 US disclosed
US-4831084-A Resin-linker combination for the solid-phase synthesis of peptides and intermediates BACHEM FEINCHEMIKALIEN A.G. (CH) 1989-05-16 US disclosed
EP-0292729-A2 Process for solid phase peptide synthesis BACHEM AG (CH) 1988-11-30 EP disclosed
US-4778757-A ADDING FIRST REAGENT OF OXIDASE, PEROXIDASE AND PHENOLIC CHROMOGEN FOLLOWED BY ADDING COUPLER; ACCURATE COLORIMETRY TOYO BOSEKI KABUSHIKI KAISHA (JP) 1988-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE GLP1R, IAPP, VIP MAOB 3979/4885PDCD1 2137/4885CD274 2715/4885
US-20030041391-A1 Agent and method for dyeing keratin fibres KRT18, AKR7A2, ADH5 MAOB 107/4885PDCD1 3400/4885CD274 3918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.