SCHEMBL4847162

SCHEMBL4847162

COc1ccc(O)cc1CO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
PDE4A P27815 1/20 0.50
PDE4B Q07343 1/20 0.50
PDE4C Q08493 1/20 0.50
PDE4D Q08499 1/20 0.50
ELANE P08246 2/20 0.49
CTSG P08311 1/20 0.49
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
ALOX15 P16050 1/20 0.45
CASP1 P29466 1/20 0.45
HTT P42858 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL9788450 0.98 MAOB (0.50) MAOBPDE4APDE4BPDE4CPDE4D
SCHEMBL29392084 0.83 MAOB (0.52) MAOBKDM4EMEN1USP2ALDH1A1
SCHEMBL178369 0.83 MAOB (0.52) MAOBKDM4EMEN1USP2ALDH1A1
SCHEMBL288669 0.83 MAOB (0.57) MAOBPDE4APDE4BPDE4CPDE4D
SCHEMBL29415192 0.83 MAOB (0.57) MAOBPDE4APDE4BPDE4CPDE4D
SCHEMBL16625523 0.83 MAOB (0.52) MAOBKDM4EMEN1USP2ALDH1A1
SCHEMBL8319257 0.82 MAOB (0.50) MAOBKDM4EMEN1USP2ALDH1A1
SCHEMBL1742531 0.79 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DALDH1A1
SCHEMBL487944 0.79 HSD17B10 (0.62) PDE4APDE4BPDE4CPDE4DHSD17B10
SCHEMBL2908313 0.79 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240681-A Composite demulsifying agent and combinations thereof and application 中国石油化工股份有限公司 2019-09-17 CN disclosed
CN-110240675-A Demulsifier and preparation method thereof and the application in the demulsification of binary combination flooding produced liquid 中国石油化工股份有限公司 2019-09-17 CN disclosed
CN-109929429-A A kind of cured optical fiber coating coating of Rapid radiating 浙江福斯特新材料研究院有限公司 2019-06-25 CN disclosed
CN-109929430-A A kind of optical fiber outer coating paint of resistant to hydrolysis 浙江福斯特新材料研究院有限公司 2019-06-25 CN disclosed
CN-104000752-B Ginger extract for stem cell protection 西姆莱斯股份公司 2018-12-14 CN disclosed
US-9343686-B2 Compound, solar cell module, and solar power generation device SHARP KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20150162547-A1 COMPOUND, SOLAR CELL MODULE, AND SOLAR POWER GENERATION DEVICE SHARP KABUSHIKI KAISHA (JP) 2015-06-11 US disclosed
US-RE40558-E1 Therapeutic uses of di-aryl acid derivatives SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-10-28 US disclosed
US-6635655-B1 Agonists or antagonists of peroxisome proliferator-activated receptors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-10-21 US disclosed
US-6376512-B1 FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-04-23 US disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
WO-1989004305-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150162547-A1 COMPOUND, SOLAR CELL MODULE, AND SOLAR POWER GENERATION DEVICE SIK1, CRY1, SIK2 MAOB 4377/4885PDE4A 3629/4885PDE4B 3285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.