Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139622 | 0.88 | MAPT (0.44) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL28956905 | 0.88 | MAPT (0.44) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL2339227 | 0.84 | MAPT (0.57) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL2805140 | 0.83 | MAPT (0.42) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL24425908 | 0.80 | MAPT (0.50) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL30488306 | 0.79 | XDH (0.54) | MAPTXDHLMNA | |
| SCHEMBL1807138 | 0.79 | XDH (0.54) | MAPTXDHLMNA | |
| SCHEMBL2827824 | 0.78 | NOTUM (0.56) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL6568018 | 0.78 | MAPT (0.66) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL28663604 | 0.78 | MAPT (0.66) | MAPTCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907297-B | Method for preparing benzodihydrofuran derivative by tandem connection of visible light catalytic 2-alkynyl aryl ether and sulfonyl chloride | 湖南警察学院 | 2024-09-24 | — | — | CN | disclosed |
| CN-114907297-A | Method for preparing benzodihydrofuran derivative by visible light catalysis of 2-alkynyl aryl ether and sulfonyl chloride in series | 湖南警察学院 | 2022-08-16 | — | — | CN | disclosed |