Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807138 | 1.00 | XDH (0.54) | XDHLMNAS1PR1S1PR3MAPT | |
| SCHEMBL932740 | 0.88 | XDH (0.54) | XDHS1PR1S1PR3 | |
| SCHEMBL24860790 | 0.87 | MAPT (0.43) | XDHLMNAS1PR1S1PR3MAPT | |
| SCHEMBL8148281 | 0.86 | CA1 (0.52) | XDHLMNAMAPT | |
| SCHEMBL31139622 | 0.85 | MAPT (0.44) | XDHLMNAMAPT | |
| SCHEMBL28956905 | 0.85 | MAPT (0.44) | XDHLMNAMAPT | |
| SCHEMBL30603423 | 0.85 | XDH (0.67) | XDH | |
| SCHEMBL28323507 | 0.85 | XDH (0.56) | XDHS1PR1S1PR3 | |
| SCHEMBL403398 | 0.85 | XDH (0.67) | XDH | |
| SCHEMBL28140004 | 0.85 | ALDH1A1 (0.52) | XDHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444697-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107563-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |