SCHEMBL2886802

SCHEMBL2886802

CC(C)(C)[PH+](c1ccccc1)C(C)(C)C.F[B-](F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
ACHE P22303 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16694347 0.89 KIF11 (0.40) MAPK1ACHEALDH1A1KIF11
SCHEMBL16694052 0.84 KIF11 (0.36) ALDH1A1KIF11
SCHEMBL2884917 0.84 MAPK1 (0.34) MAPK1
SCHEMBL2881944 0.84 MAPK1 (0.34) MAPK1
SCHEMBL700460 0.82 MAPK1 (0.33) MAPK1
SCHEMBL16694153 0.81 KIF11 (0.38) MAPK1ACHEALDH1A1KIF11
SCHEMBL16694164 0.79 ACHE (0.35) ACHE
SCHEMBL16694561 0.79 TSHR (0.37) ACHE
SCHEMBL16694307 0.77 TSHR (0.41) MAPK1ACHEALDH1A1KIF11
SCHEMBL29591821 0.77 ACHE (0.41) MAPK1ACHEALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903475-B Preparation of large-area self-supporting rigidifying composite film and application of large-area self-supporting rigidifying composite film in space inflation unfolding structure 哈尔滨工业大学 2024-09-03 CN claimed
CN-117903475-A Preparation of large-area self-supporting rigidifying composite film and application of large-area self-supporting rigidifying composite film in space inflation unfolding structure 哈尔滨工业大学 2024-04-19 CN claimed
CN-109438511-B Method for synthesizing di-tert-butyl phenyl phosphonium tetrafluoroborate 河南省科学院化学研究所有限公司 2020-11-06 CN claimed
US-7847126-B2 prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example LANXESS DEUTSCHLAND GMBH (DE) 2010-12-07 US claimed
EP-1354886-B1 Process for the preparation of tertiary phosphines SALTIGO GMBH (DE) 2009-08-26 EP claimed
US-20070299273-A1 prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example LANXESS DEUTSCHLAND GMBH (DE) 2007-12-27 US claimed
US-20030229240-A1 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2003-12-11 US claimed
EP-1354886-A1 Process for the preparation of tertiary phosphines Bayer Aktiengesellschaft (DE) 2003-10-22 EP claimed
CN-117903475-B Preparation of large-area self-supporting rigidifying composite film and application of large-area self-supporting rigidifying composite film in space inflation unfolding structure 哈尔滨工业大学 2024-09-03 CN disclosed
CN-117903475-A Preparation of large-area self-supporting rigidifying composite film and application of large-area self-supporting rigidifying composite film in space inflation unfolding structure 哈尔滨工业大学 2024-04-19 CN disclosed
CN-117088776-A Method for preparing 2-nitrobiphenyl compound 江西天宇化工有限公司 2023-11-21 CN disclosed
CN-110325513-B Process for preparing substituted biphenyls 巴斯夫欧洲公司 2023-11-03 CN disclosed
EP-3583093-B1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BASF SE (DE) 2021-04-14 EP disclosed
CN-109438511-B Method for synthesizing di-tert-butyl phenyl phosphonium tetrafluoroborate 河南省科学院化学研究所有限公司 2020-11-06 CN disclosed
EP-1354886-B1 Process for the preparation of tertiary phosphines SALTIGO GMBH (DE) 2009-08-26 EP disclosed
US-20070299273-A1 prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example LANXESS DEUTSCHLAND GMBH (DE) 2007-12-27 US disclosed
US-7230136-B2 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2007-06-12 US disclosed
US-20030229240-A1 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2003-12-11 US disclosed
EP-1354886-A1 Process for the preparation of tertiary phosphines Bayer Aktiengesellschaft (DE) 2003-10-22 EP disclosed
EP-1354886-A1 Process for the preparation of tertiary phosphines Bayer Aktiengesellschaft (DE) 2003-10-22 EP disclosed