Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868398 | 1.00 | SIGMAR1 (0.39) | SIGMAR1KCNH2MAOAGRIK1MAOB | |
| SCHEMBL28508158 | 0.91 | FDFT1 (0.44) | — | |
| SCHEMBL28508156 | 0.91 | FDFT1 (0.44) | — | |
| SCHEMBL28505333 | 0.86 | KDM4E (0.37) | SIGMAR1KCNH2MAOB | |
| SCHEMBL28505335 | 0.86 | KDM4E (0.37) | SIGMAR1KCNH2MAOB | |
| SCHEMBL28503369 | 0.76 | — | — | |
| SCHEMBL28435829 | 0.70 | MAOA (0.45) | SIGMAR1MAOAMAOB | |
| SCHEMBL28432437 | 0.67 | CNR2 (0.42) | KCNH2HTR2A | |
| Bromide SCHEMBL10928757 | 0.64 | SIGMAR1 (0.50) | SIGMAR1KCNH2MAOAMAOBHTR2A | |
| SCHEMBL585515 | 0.63 | SIGMAR1 (0.45) | SIGMAR1KCNH2GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111333-B | Chiral gem-disilyl alkane compound and synthesis method and application thereof | 浙江大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-109111333-A | It is a kind of chiral together with two silicon substrate alkane compounds and its synthetic method and application | 浙江大学 | 2019-01-01 | — | — | CN | disclosed |