Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26659359 | 0.84 | MAPT (0.55) | PARP1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL26659387 | 0.84 | MAPT (0.55) | PARP1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL5459512 | 0.84 | PARP1 (0.65) | PARP1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL12789348 | 0.84 | MEN1 (0.53) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL5177152 | 0.84 | PARP1 (0.65) | PARP1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL15332089 | 0.83 | PARP1 (0.56) | PARP1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL15332092 | 0.83 | PARP1 (0.56) | PARP1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL14482123 | 0.82 | MEN1 (0.51) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL14482118 | 0.82 | MEN1 (0.51) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL14482122 | 0.82 | MEN1 (0.51) | RAB9ANPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876941-B | Fused tricyclic class compound and its application | 南京汇诚制药有限公司 | 2019-02-01 | — | — | CN | disclosed |