Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.65 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459512 | 1.00 | PARP1 (0.65) | PARP1NAPRTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8733663 | 0.89 | PARP1 (0.75) | PARP1HSD17B10KDM4EALDH1A1CYP1A2 | |
| SCHEMBL10348048 | 0.87 | NAPRT (0.53) | PARP1NAPRTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5177143 | 0.85 | PARP1 (0.57) | PARP1NAPRTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL26659387 | 0.85 | MAPT (0.55) | PARP1KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL26659359 | 0.85 | MAPT (0.55) | PARP1KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5177147 | 0.85 | PARP1 (0.57) | PARP1NAPRTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL2322466 | 0.84 | NAPRT (0.59) | PARP1NAPRTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL2322470 | 0.84 | NAPRT (0.59) | PARP1NAPRTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL2358808 | 0.84 | NAPRT (0.59) | PARP1NAPRTHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070196360-A1 | SUCCINIMIDE AND MALEIMIDE DERIVATIVES AND THEIR USE AS TOPOISOMERASE II CATALYTIC INHIBITORS | TOPOTARGET A/S | 2007-08-23 | — | — | US | disclosed |
| EP-1602481-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2007-05-30 | — | — | EP | disclosed |
| EP-1203659-B1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO LTD (JP) | 2006-05-17 | — | — | EP | disclosed |
| EP-1373494-B1 | SUCCINIMIDE AND MALEIMIDE DERIVATIVES AND THEIR USE AS TOPOISOMERASE II CATALYTIC INHIBITORS | TOPOTARGET AS (DK) | 2006-03-01 | — | — | EP | disclosed |
| EP-1602481-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-1371500-B1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO LTD (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-6939658-B2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-06 | — | — | US | disclosed |
| EP-1048457-B1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO LTD (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6824946-B2 | SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1031414-B1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6509132-B1 | Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| WO-2002078679-A2 | SUCCINIMIDE AND MALEIMIDE DERIVATIVES AND THEIR USE AS TOPOISOMERASE II CATALYTIC INHIBITORS | TOPO TARGET APS (DK) | 2002-10-10 | — | — | WO | disclosed |
| US-6455224-B1 | SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE | FUJI PHOTO FILM CO., LTD. (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020068241-A1 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2002-06-06 | — | — | US | disclosed |
| EP-1203659-A2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2002-05-08 | — | — | EP | disclosed |
| EP-1136281-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2001-09-26 | — | — | EP | disclosed |
| EP-1048457-A2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-1031414-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0179448-B1 | PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE | MITSUBISHI KASEI CORPORATION (JP) | 1990-04-18 | — | — | EP | disclosed |
| EP-0179448-A2 | Photosensitive planographic printing plate | MITSUBISHI KASEI CORPORATION (JP) | 1986-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196360-A1 | SUCCINIMIDE AND MALEIMIDE DERIVATIVES AND THEIR USE AS TOPOISOMERASE II CATALYTIC INHIBITORS | TOP2A, TOP2B, TOP1 | PARP1 18/4885NAPRT 566/4885HSD17B10 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.