SCHEMBL26659387

SCHEMBL26659387

C/C(=C\C(=O)O)C(=O)Nc1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.55
▸ ALDH1A1 P00352 4/20 0.55
▸ MEN1 O00255 2/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ CYP1A1 P04798 2/20 0.55
▸ TSHR P16473 2/20 0.55
▸ CA12 O43570 1/20 0.55
▸ BRD4 O60885 1/20 0.55
▸ NR1I2 O75469 1/20 0.55
▸ CA1 P00915 1/20 0.55
▸ CA2 P00918 1/20 0.55
▸ MB P02144 1/20 0.55
▸ CA3 P07451 1/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ RARG P13631 1/20 0.55
▸ ALOX5AP P20292 1/20 0.55
▸ CA4 P22748 1/20 0.55
▸ CA7 P43166 1/20 0.55
▸ NR1I3 Q14994 1/20 0.55
▸ CA9 Q16790 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26659359 1.00 MAPT (0.55) MAPTALDH1A1MEN1KMT2ACYP1A1
SCHEMBL5459512 0.85 PARP1 (0.65) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL5177152 0.85 PARP1 (0.65) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL15332089 0.84 PARP1 (0.56) MAPTALDH1A1MEN1KMT2APARP1
SCHEMBL28868514 0.84 PARP1 (0.52) MAPTALDH1A1MEN1KMT2APARP1
SCHEMBL15332092 0.84 PARP1 (0.56) MAPTALDH1A1MEN1KMT2APARP1
SCHEMBL14044782 0.81 NMT1 (0.63) MAPTALDH1A1MEN1KMT2APARP1
SCHEMBL26659471 0.80 PARP1 (0.68) MAPTALDH1A1MEN1KMT2APARP1
SCHEMBL26659454 0.80 PARP1 (0.68) MAPTALDH1A1MEN1KMT2APARP1
SCHEMBL8733663 0.79 PARP1 (0.75) MAPTALDH1A1MEN1KMT2APARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KANEKA CORPORATION (JP) 2023-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KDM5C, DHX15, KDM5A MAPT 969/4885ALDH1A1 476/4885MEN1 4568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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