Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868627 | 0.89 | GPR119 (0.38) | USP30UCHL1KMT2AGPR119 | |
| SCHEMBL30021366 | 0.87 | GPR119 (0.46) | MEN1ALDH1A1KMT2AGPR119 | |
| SCHEMBL20294497 | 0.87 | GPR119 (0.46) | MEN1ALDH1A1KMT2AGPR119 | |
| SCHEMBL2792027 | 0.79 | GPR119 (0.43) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2792024 | 0.79 | GPR119 (0.43) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26636634 | 0.76 | KDM4E (0.45) | KMT2AGPR119 | |
| SCHEMBL30735089 | 0.76 | KDM4E (0.45) | KMT2AGPR119 | |
| SCHEMBL193960 | 0.75 | MEN1 (0.45) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31652058 | 0.75 | USP30 (0.45) | USP30UCHL1MEN1ALDH1A1MAPT | |
| SCHEMBL20284097 | 0.75 | GPR119 (0.43) | USP30MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232109-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2022-10-25 | — | — | CN | disclosed |