Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868520 | 0.89 | USP30 (0.42) | GPR119USP30UCHL1KMT2A | |
| SCHEMBL20294497 | 0.89 | GPR119 (0.46) | GPR119GRM5KDM4EKMT2A | |
| SCHEMBL30021366 | 0.89 | GPR119 (0.46) | GPR119GRM5KDM4EKMT2A | |
| SCHEMBL21722989 | 0.80 | STS (0.43) | GPR119NAMPTRORCALDH2USP30 | |
| SCHEMBL25263787 | 0.77 | RORC (0.42) | GPR119NAMPTRORCALDH2KDM4E | |
| SCHEMBL22462862 | 0.77 | GPR119 (0.41) | GPR119RORCALDH2USP30KMT2A | |
| SCHEMBL29693467 | 0.77 | GPR119 (0.41) | GPR119RORCALDH2USP30KMT2A | |
| SCHEMBL30735089 | 0.76 | KDM4E (0.45) | GPR119KDM4EKMT2A | |
| SCHEMBL22530217 | 0.76 | STS (0.46) | GPR119NAMPTRORCALDH2KDM4E | |
| SCHEMBL30734613 | 0.76 | GPR119 (0.44) | GPR119KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232109-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2022-10-25 | — | — | CN | disclosed |