Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850069 | 0.76 | RORC (0.48) | RORCGPR119CD274PDCD1LG2 | |
| SCHEMBL27253377 | 0.75 | RORC (0.56) | RORCPARP1 | |
| SCHEMBL30620505 | 0.75 | RORC (0.53) | RORCPARP1 | |
| SCHEMBL23003391 | 0.75 | CYP3A4 (0.52) | RORCGPR119 | |
| SCHEMBL28868549 | 0.74 | CD274 (0.35) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23850532 | 0.73 | RORC (0.55) | RORCPARP1 | |
| SCHEMBL30013334 | 0.73 | GPR183 (0.54) | RORCGPR119 | |
| SCHEMBL19173661 | 0.72 | RORC (0.53) | RORCGPR119OPRD1OPRK1 | |
| SCHEMBL29669150 | 0.71 | RORC (0.48) | RORCGPR119CD274PDCD1LG2PDCD1 | |
| SCHEMBL20238623 | 0.71 | RORC (0.48) | RORCGPR119CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232109-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2022-10-25 | — | — | CN | disclosed |