Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL163452 | 0.84 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL711677 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL2854923 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL1449856 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL1006745 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL8091612 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL5573865 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL3437057 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL20541362 | 0.82 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL28739842 | 0.82 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109312054-A | Fibre reinforced composites two-liquid type composition epoxy resin and fibre reinforced composites | 东丽株式会社 | 2019-02-05 | — | — | CN | disclosed |