SCHEMBL28868686

SCHEMBL28868686

NCCCCCCCCCCCCCCCCCCCOC(=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.42
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA9 Q16790 4/20 0.42
HDAC6 Q9UBN7 1/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.37
PLG P00747 1/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
SLC6A2 P23975 1/20 0.37
RECQL P46063 1/20 0.37
SLC6A3 Q01959 1/20 0.37
KMT2A Q03164 1/20 0.37
CES2 O00748 1/20 0.36
PAOX Q6QHF9 2/20 0.35
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
CA3 P07451 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28726906 0.98 CA12 (0.40) CA12CA1CA2CA9HDAC6
SCHEMBL2093021 0.91 HDAC6 (0.36) CA12CA1CA2CA9HDAC6
SCHEMBL19379541 0.87 CES2 (0.39) ALDH1A1MEN1KMT2ACES2TSHR
SCHEMBL5548192 0.85 HDAC6 (0.53) CA12CA1CA2CA9HDAC6
SCHEMBL2264321 0.82 IDO1 (0.32) HDAC6
SCHEMBL28903671 0.82 CES2 (0.34) ALDH1A1MEN1KMT2ACES2TSHR
SCHEMBL28390013 0.82 HDAC1 (0.38) HDAC6MEN1KMT2ACES2
SCHEMBL28740119 0.82 CA1 (0.35) CA12CA1CA2CA9HDAC6
SCHEMBL6061006 0.81 ACHE (0.42) ALDH1A1CES2TSHRCYP3A4
SCHEMBL7717988 0.80 CA12 (0.40) CA12CA1CA2CA9HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109073647-A Droplet interior surface engineering for capture of molecular targets 斯特拉斯堡大学 2018-12-21 CN disclosed