Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.48 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.36 |
| ▸ | CDK9 | P50750 | 9/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29892387 | 0.87 | SOS1 (0.47) | SOS1 | |
| SCHEMBL27118608 | 0.87 | SOS1 (0.47) | SOS1 | |
| SCHEMBL28868855 | 0.84 | ACHE (0.41) | SOS1QDPRFGFR4CCNT1CDK9 | |
| SCHEMBL27143571 | 0.79 | SOS1 (0.49) | SOS1QDPRMAPT | |
| SCHEMBL28891923 | 0.78 | SOS1 (0.44) | SOS1QDPRFGFR4CCNT1CDK9 | |
| SCHEMBL30014528 | 0.77 | PSMB5 (0.59) | SOS1PSMB5 | |
| SCHEMBL4335947 | 0.75 | QDPR (0.48) | QDPRCCNT1CDK9MAPT | |
| SCHEMBL27124483 | 0.74 | SOS1 (0.48) | SOS1CCNT1CDK9PSMB5 | |
| SCHEMBL30015103 | 0.73 | SOS1 (0.51) | SOS1 | |
| SCHEMBL30014724 | 0.72 | SOS1 (0.49) | SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232114-B | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-115232111-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232108-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |