Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.76 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22666944 | 0.90 | ELANE (0.74) | ELANEKMT2AMEN1MAPTHTT | |
| SCHEMBL6767042 | 0.88 | ELANE (0.68) | ELANEESR1KMT2AMEN1MAPT | |
| SCHEMBL6765870 | 0.88 | ELANE (0.68) | ELANEESR1KMT2AMEN1MAPT | |
| SCHEMBL8863149 | 0.86 | ELANE (0.57) | ELANEESR1KMT2AMEN1BCL9 | |
| SCHEMBL5935043 | 0.86 | ELANE (0.66) | ELANEESR1KMT2AMEN1MAPT | |
| SCHEMBL10424760 | 0.86 | ELANE (1.00) | ELANEESR1KMT2AMEN1MAPT | |
| SCHEMBL62921 | 0.86 | BCL9 (0.59) | ELANEESR1KMT2AMEN1MAPT | |
| SCHEMBL20769806 | 0.86 | BCL9 (0.59) | ELANEESR1KMT2AMEN1MAPT | |
| SCHEMBL8384348 | 0.85 | ELANE (0.55) | ELANEESR1KMT2AMEN1MAPT | |
| SCHEMBL22666945 | 0.85 | ELANE (0.68) | ELANEESR1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232114-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232108-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |