Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28352738 | 1.00 | GSR (0.43) | GSRCPB2PTGS1SLC7A11DPP7 | |
| Lysine SCHEMBL27660749 | 0.94 | GSR (0.48) | GSRCPB2DPP7DPP4DPP8 | |
| Lysine SCHEMBL4956225 | 0.94 | GSR (0.48) | GSRCPB2DPP7DPP4DPP8 | |
| Lysine SCHEMBL21494167 | 0.94 | GSR (0.48) | GSRCPB2DPP7DPP4DPP8 | |
| Lysine SCHEMBL17580033 | 0.94 | GSR (0.48) | GSRCPB2DPP7DPP4DPP8 | |
| Lysine SCHEMBL3387882 | 0.94 | GSR (0.48) | GSRCPB2DPP7DPP4DPP8 | |
| Lysine SCHEMBL21494166 | 0.94 | GSR (0.48) | GSRCPB2DPP7DPP4DPP8 | |
| Lysine SCHEMBL8561773 | 0.92 | GSR (0.46) | GSRCPB2PTGS1SLC7A11DPP7 | |
| Lysine SCHEMBL20678166 | 0.92 | GSR (0.50) | GSRCPB2PTGS1SLC7A11DPP7 | |
| Lysine SCHEMBL9167629 | 0.92 | GSR (0.36) | GSRSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232715-A | The ultrashort peptide of antioxidizing and its application | 大连理工大学 | 2019-01-18 | — | — | CN | disclosed |