Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28352738 | 0.92 | GSR (0.43) | GSRSLC7A5 | |
| Lysine SCHEMBL28868906 | 0.92 | GSR (0.43) | GSRSLC7A5 | |
| Lysine SCHEMBL17685564 | 0.91 | GSR (0.43) | GSRSLC7A5 | |
| Lysine SCHEMBL27639977 | 0.88 | GSR (0.47) | GSR | |
| Lysine SCHEMBL659927 | 0.88 | GSR (0.47) | GSR | |
| Lysine SCHEMBL5801871 | 0.87 | GSR (0.37) | GSRSLC7A5 | |
| Leucine SCHEMBL4616828 | 0.87 | SLC7A5 (0.38) | SLC7A5 | |
| Lysine SCHEMBL21494167 | 0.87 | GSR (0.48) | GSRSLC7A5 | |
| Lysine SCHEMBL4450695 | 0.87 | GSR (0.48) | GSRSLC7A5 | |
| Lysine SCHEMBL20641479 | 0.87 | GSR (0.48) | GSRSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654080-A1 | PEPTIDES THAT MIMIC gp120 HIV EPITOPE | MEDICAL RESEARCH COUNCIL (GB) | 1995-05-24 | — | — | EP | claimed |
| EP-0654080-A1 | PEPTIDES THAT MIMIC gp120 HIV EPITOPE | MEDICAL RESEARCH COUNCIL (GB) | 1995-05-24 | — | — | EP | disclosed |
| EP-0654080-A1 | PEPTIDES THAT MIMIC gp120 HIV EPITOPE | MEDICAL RESEARCH COUNCIL (GB) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994002614-A1 | PEPTIDES THAT MIMIC gp120 HIV EPITOPE | MEDICAL RESEARCH COUNCIL (GB) | 1994-02-03 | — | — | WO | disclosed |