Piperidine

Piperidine

SCHEMBL28869230

C1CCNCC1.COC(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.40
CXCR4 P61073 1/20 0.40
EPHX1 P07099 2/20 0.35
CA2 P00918 1/20 0.34
CHKA P35790 1/20 0.34
SLC6A1 P30531 2/20 0.33
TSHR P16473 2/20 0.33
SLC6A11 P48066 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL28337030 0.97 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2CXCR4EPHX1SLC6A1
Piperidine SCHEMBL28869229 0.84 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2CXCR4EPHX1CA2
Piperidine SCHEMBL3849398 0.83 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2EPHX1CA2CHKA
Cyclohexane SCHEMBL11243795 0.83 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRLMNAKMT2A
Cyclopropane SCHEMBL18825318 0.83
Piperidine SCHEMBL28645406 0.82 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2CXCR4EPHX1CA2
Pyrrolidine SCHEMBL29788209 0.81 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CXCR4EPHX1CA2
Piperidine SCHEMBL7718759 0.81 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2CXCR4EPHX1CA2
Pyrrolidine SCHEMBL9400616 0.81 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2CXCR4EPHX1CA2
Piperidine SCHEMBL29043025 0.80 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CXCR4EPHX1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293517-A The method for preparing template 庄信万丰股份有限公司 2019-02-01 CN disclosed