Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742482 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29472962 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10312043 | 0.80 | PDE5A (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29670513 | 0.80 | PDE5A (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL20815523 | 0.80 | PDE5A (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL940015 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL940017 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17687836 | 0.74 | GRM4 (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17687833 | 0.74 | GRM4 (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL466309 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311825-A | Novel 2,4,6- tri- replaces s-triazine and its preparation method and application | 南京世其医药科技有限公司 | 2019-02-05 | — | — | CN | disclosed |