Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20815523 | 1.00 | PDE5A (0.46) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL29670513 | 0.96 | PDE5A (0.46) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL28798157 | 0.84 | MEN1 (0.54) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL28742483 | 0.82 | TRPA1 (0.44) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL21008079 | 0.82 | LMNA (0.53) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL596715 | 0.81 | ALDH1A1 (0.46) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL596716 | 0.81 | ALDH1A1 (0.46) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL28869271 | 0.80 | KDM4E (0.48) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| SCHEMBL28742482 | 0.80 | KDM4E (0.48) | PDE5AMEN1KMT2AGRM4ALDH1A1 | |
| (Z)-1,2-Diphenylethene SCHEMBL1376696 | 0.75 | MAOB (0.69) | MEN1KMT2AALDH1A1MAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190042-A1 | NOVEL 2,4,6-TRISUBSTITUTED S-TRIAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | ALUDA PHARMACEUTICALS, INC. | 2020-06-18 | — | — | US | disclosed |
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CALIFORNIA CAPITAL EQUITY, LLC (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | STK25, STK35, SGK2 | PDE5A 1708/4885MEN1 4391/4885KMT2A 1102/4885 |
| US-20200190042-A1 | NOVEL 2,4,6-TRISUBSTITUTED S-TRIAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | VIM, HASPIN, WASF2 | PDE5A 2780/4885MEN1 1503/4885KMT2A 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.