SCHEMBL2886943

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2315507	0.86	LMNA (0.56)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL2894859	0.85	LMNA (0.55)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL2316271	0.84	LMNA (0.51)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL2312239	0.83	LMNA (0.50)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL7919943	0.83	LMNA (0.50)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL5029502	0.83	CYP11B2 (0.46)	TYK2HTTMEN1KMT2AMAPT
	SCHEMBL14922695	0.83	IL2 (0.47)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL5029725	0.83	IL2 (0.56)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL2314359	0.82	LMNA (0.49)	LMNAIL2JAK2JAK1TYK2
	SCHEMBL2893143	0.82	IL2 (0.46)	LMNAIL2JAK2JAK1TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.