Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637969 | 0.90 | TDP1 (0.62) | SIRT2TDP1ATML3MBTL1HDAC2 | |
| SCHEMBL24326634 | 0.86 | TDP1 (0.69) | SIRT2TDP1ATML3MBTL1HDAC2 | |
| SCHEMBL6325567 | 0.84 | SIRT2 (0.75) | SIRT2TDP1ATML3MBTL1LMNA | |
| SCHEMBL24326051 | 0.84 | TDP1 (0.68) | SIRT2TDP1ATML3MBTL1HDAC2 | |
| SCHEMBL10173253 | 0.83 | SMN1; SMN2 (0.59) | TDP1ATML3MBTL1MAPTLMNA | |
| SCHEMBL16975850 | 0.82 | SMN1; SMN2 (0.71) | TDP1ATML3MBTL1HDAC2HDAC8 | |
| SCHEMBL24326628 | 0.82 | TDP1 (0.64) | SIRT2TDP1ATML3MBTL1HDAC2 | |
| SCHEMBL11920075 | 0.81 | TDP1 (0.62) | SIRT2TDP1ATML3MBTL1HDAC2 | |
| SCHEMBL19835591 | 0.81 | TDP1 (0.62) | SIRT2TDP1ATML3MBTL1HDAC2 | |
| SCHEMBL14679168 | 0.81 | TDP1 (0.62) | TDP1ATML3MBTL1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | claimed |
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |