Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886058 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATSHRNPY5R | |
| SCHEMBL90848 | 0.84 | POLB (0.41) | ALDH1A1MEN1KMT2ATSHRNPY5R | |
| SCHEMBL2898453 | 0.84 | NPY5R (0.45) | ALDH1A1NPY5RMAPTPOLB | |
| SCHEMBL2901646 | 0.84 | NPY5R (0.45) | ALDH1A1NPY5RMAPTPOLB | |
| SCHEMBL2901644 | 0.84 | NPY5R (0.45) | ALDH1A1NPY5RMAPTPOLB | |
| SCHEMBL22217050 | 0.78 | MEN1 (0.43) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL90843 | 0.77 | NPY5R (0.47) | ALDH1A1MEN1KMT2ANPY5RPOLB | |
| SCHEMBL90846 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ATSHRNPY5R | |
| SCHEMBL13952030 | 0.77 | MAPT (0.47) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL2884413 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ATSHRNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691860-B2 | Sulfonamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-04-06 | — | — | US | disclosed |
| US-20080161326-A1 | Novel Sulfone Amide Amide Derivatives | MSD K.K. (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1719765-A1 | NOVEL SULFONE AMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161326-A1 | Novel Sulfone Amide Amide Derivatives | NPY1R, NPY2R, NPY5R | ALDH1A1 1680/4885MEN1 426/4885KMT2A 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.