Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2898453 | 1.00 | NPY5R (0.45) | NPY5RTP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL2901644 | 1.00 | NPY5R (0.45) | NPY5RTP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL2886966 | 0.84 | ALDH1A1 (0.44) | NPY5RPOLBALDH1A1MAPT | |
| SCHEMBL2886058 | 0.84 | ALDH1A1 (0.44) | NPY5RPOLBALDH1A1MAPT | |
| SCHEMBL90843 | 0.82 | NPY5R (0.47) | NPY5RSMN1; SMN2POLBALDH1A1HSD17B10 | |
| SCHEMBL90846 | 0.82 | ALDH1A1 (0.50) | NPY5RSMN1; SMN2ALDH1A1HSD17B10CA12 | |
| SCHEMBL594952 | 0.82 | ALDH1A1 (0.50) | NPY5RSMN1; SMN2ALDH1A1HSD17B10CA12 | |
| SCHEMBL2884413 | 0.82 | ALDH1A1 (0.50) | NPY5RSMN1; SMN2ALDH1A1HSD17B10CA12 | |
| SCHEMBL12048931 | 0.81 | CA12 (0.50) | NPY5RSMN1; SMN2ALDH1A1HPGDCA12 | |
| SCHEMBL12836912 | 0.81 | NPY5R (0.46) | NPY5RSMN1; SMN2ALDH1A1HSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411355-B1 | PROCESS FOR THE PREPARATION OF TRANS-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID | SIEGFRIED AG (CH) | 2020-10-28 | — | — | EP | disclosed |
| WO-2017134212-A1 | PROCESS FOR THE PREPARATION OF TRANS-4-AMINO-1-CYCLOHEXANECARBOXILIC ACID AND ITS DERIVATIVES | SIEGFRIED AG (CH) | 2017-08-10 | — | — | WO | disclosed |
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| CN-101104598-B | Process for preparing trans-4-amino-1-cyclohexanecarboxilic acid derivatives | SHIONOGI & CO | 2011-06-15 | — | — | CN | disclosed |
| US-20110039802-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2011-02-17 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| CN-1821217-B | Process for producing trans-4-amino-1-cyclohexanecarboxylic acid derivative | SHIONOGI & CO | 2010-09-29 | — | — | CN | disclosed |
| US-7795471-B2 | Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-7781461-B2 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2010-08-24 | — | — | US | disclosed |
| US-7314950-B2 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | SHIONOGI & CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314950-B2 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | SHIONOGI & CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314950-B2 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | SHIONOGI & CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-20070015762-A1 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2007-01-18 | — | — | US | disclosed |
| CN-1821217-A | Process for producing trans-4-amino-1-cyclohexanecarboxylic acid derivative | SHIONOGI & CO (JP) | 2006-08-23 | — | — | CN | disclosed |
| US-20050222255-A1 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | SHIONOGI & CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| CN-1639096-A | Process for producing trans-4-amino-1-cyclohexanecarboxylic acid derivative | SHIONOGI & CO (JP) | 2005-07-13 | — | — | CN | disclosed |
| EP-1484301-A1 | PROCESS FOR PRODUCING trans-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2004-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015762-A1 | NPY Y5 antagonist | NPY5R, NPY1R, NPY2R | NPY5R 1/4885TP53 4449/4885SMN1; SMN2 2213/4885 |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | NPY5R 1/4885TP53 4417/4885SMN1; SMN2 2197/4885 |
| US-20110039802-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | NPY5R 1/4885TP53 4486/4885SMN1; SMN2 2251/4885 |
| US-20050222255-A1 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | ACMSD, AADAT, AAAS | NPY5R 4669/4885TP53 2564/4885SMN1; SMN2 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.