Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128193 | 0.84 | CA1 (0.56) | CA1CA2CA12CA4CA7 | |
| SCHEMBL29970206 | 0.84 | CA1 (0.56) | CA1CA2CA12CA4CA7 | |
| Hydrochloric Acid SCHEMBL31037950 | 0.82 | CA1 (0.54) | CA1CA2CA12CA4CA7 | |
| Hydrochloric Acid SCHEMBL3284355 | 0.82 | CA1 (0.54) | CA1CA2CA12CA4CA7 | |
| SCHEMBL752611 | 0.82 | F2 (0.48) | ALDH1A1HPGDLMNAL3MBTL1TSHR | |
| SCHEMBL6891909 | 0.81 | CA1 (0.48) | CA1CA2CA12CA4CA7 | |
| SCHEMBL527995 | 0.81 | PARP1 (0.56) | CA1CA2CA12CA4CA7 | |
| SCHEMBL28216624 | 0.80 | MEN1 (0.48) | ALDH1A1HPGDHTTSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL6341904 | 0.80 | BLM (0.50) | ALDH1A1HPGDLMNATSHRKLK1 | |
| SCHEMBL28216057 | 0.78 | HTT (0.50) | ALDH1A1HTTPARP1F10PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109468659-A | The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase | 云南师范大学 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456273-A | The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase | 云南师范大学 | 2019-03-12 | — | — | CN | disclosed |