Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062441 | 0.86 | PARP1 (0.54) | PARP1BCAT2HPGDALDH1A1HTT | |
| SCHEMBL4117324 | 0.86 | PARP1 (0.54) | PARP1BCAT2HPGDALDH1A1HTT | |
| SCHEMBL5242291 | 0.86 | PARP1 (0.51) | PARP1BCAT2HPGDALDH1A1HTT | |
| SCHEMBL29706670 | 0.86 | LMNA (0.52) | PARP1BCAT2HPGDALDH1A1HTT | |
| SCHEMBL5582519 | 0.85 | PARP1 (0.53) | PARP1BCAT2HPGDALDH1A1HTT | |
| SCHEMBL28323667 | 0.84 | LMNA (0.49) | PARP1BCAT2HPGDALDH1A1HTT | |
| SCHEMBL264288 | 0.84 | IRAK4 (0.63) | HPGDALDH1A1HTTIRAK4CTSD | |
| SCHEMBL29423358 | 0.84 | IRAK4 (0.63) | HPGDALDH1A1HTTIRAK4CTSD | |
| SCHEMBL528360 | 0.84 | HTT (0.48) | PARP1BCAT2HPGDALDH1A1HTT | |
| SCHEMBL1957953 | 0.83 | SMN1; SMN2 (0.56) | HPGDALDH1A1HTTCTSDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| US-20220296722-A1 | CONJUGATES AND CONJUGATES FOR USE IN PREVENTING OR TREATING OF BRAIN DAMAGE AND NEURODEGENERATIVE DISEASES | MEDICORTEX FINLAND OY (FI) | 2022-09-22 | — | — | US | disclosed |
| EP-4021510-A2 | CONJUGATES AND CONJUGATES FOR USE IN PREVENTING OR TREATING OF BRAIN DAMAGE AND NEURODEGENERATIVE DISEASES | Medicortex Finland Oy (FI) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021038125-A2 | CONJUGATES AND CONJUGATES FOR USE IN PREVENTING OR TREATING OF BRAIN DAMAGE AND NEURODEGENERATIVE DISEASES | MEDICORTEX FINLAND OY (FI) | 2021-03-04 | — | — | WO | disclosed |
| CN-109457268-A | A kind of method of electro-catalysis benzamide compound synthesis benzoxazoles | 福建医科大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-109369555-A | A kind of method of microwave radiation benzamide compound synthesis benzoxazoles in water phase | 福建医科大学 | 2019-02-22 | — | — | CN | disclosed |
| EP-2536286-A1 | INHIBITORS AND METHODS OF INHIBITING BACTERIAL AND VIRAL PATHOGENS | Siga Technologies, Inc. (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103375-A1 | INHIBITORS AND METHODS OF INHIBITING BACTERIAL AND VIRAL PATHOGENS | SIGA TECHNOLOGIES, INC. (US) | 2011-08-25 | — | — | WO | disclosed |
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296722-A1 | CONJUGATES AND CONJUGATES FOR USE IN PREVENTING OR TREATING OF BRAIN DAMAGE AND NEURODEGENERATIVE DISEASES | BDNF, PYGB, SI | PARP1 713/4885BCAT2 2020/4885HPGD 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.