Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.44 |
| ▸ | CBFB | Q13951 | 5/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010831 | 1.00 | PDE3B (0.44) | PDE3BPDE3ACBFBMAPKAPK2RPS6KA3 | |
| SCHEMBL30212441 | 0.87 | CBFB (0.47) | PDE3BPDE3ACBFBMAPKAPK2RPS6KA3 | |
| SCHEMBL19751457 | 0.83 | PDE3B (0.44) | PDE3BPDE3AMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL30011367 | 0.83 | MAPKAPK2 (0.39) | PDE3BPDE3AMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL27752625 | 0.83 | MAPKAPK2 (0.39) | PDE3BPDE3AMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL28869893 | 0.83 | MAPKAPK2 (0.39) | PDE3BPDE3AMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL31093789 | 0.75 | F11 (0.47) | PDE3BPDE3AMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL4137137 | 0.75 | F11 (0.47) | PDE3BPDE3AMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL25310874 | 0.74 | GRIA1 (0.37) | CBFBPARP1 | |
| SCHEMBL30511383 | 0.74 | GRIA1 (0.37) | CBFBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232121-B | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115232121-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2022-10-25 | — | — | CN | disclosed |