SCHEMBL28870

SCHEMBL28870

C#Cc1ccccc1C#C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.36
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
APP P05067 1/20 0.32
CYP2A6 P11509 1/20 0.31
ALOX12 P18054 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549283 1.00 HDAC8 (0.36) HDAC8TSHRLMNAAPPCYP2A6
SCHEMBL30185685 0.96 HDAC8 (0.35) HDAC8TSHRLMNAAPP
SCHEMBL19024654 0.90 ALDH1A1 (0.39) HDAC8TSHRCYP1A1CYP1B1ALDH1A1
Formaldehyde SCHEMBL27643337 0.90 HDAC8 (0.32) HDAC8TSHRLMNA
SCHEMBL207404 0.85 HDAC8 (0.30) HDAC8
SCHEMBL1803188 0.85 TSHR (0.50) TSHRKDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL10582118 0.85 HDAC8 (0.30) HDAC8
SCHEMBL7932656 0.83 MEN1 (0.33) HDAC8TSHRLMNACYP2A6KDM4E
SCHEMBL28798662 0.83 ALDH1A1 (0.47) TSHRLMNAKDM4ENPC1ALDH1A1
SCHEMBL876190 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 868 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713026-A1 LONG-ACTING PAIN-RELIEF FORMULATION Centre National de la Recherche Scientifique (FR) 2026-03-25 EP claimed
US-20230302441-A1 WELL DEFINED QUATERNARY AMMONIUM FUNCTIONALIZED QUATERPHENYLENE POLYMER DERIVATIVES FOR LOW AND HIGH TEMPERATURE POLYMER ELECTROLYTE MEMBRANE FUEL CELLS ADVENT TECHNOLOGIES HOLDINGS, INC. 2023-09-28 US claimed
WO-2023183720-A2 WELL DEFINED QUATERNARY AMMONIUM FUNCTIONALIZED QUATERPHENYLENE POLYMER DERIVATIVES FOR LOW AND HIGH TEMPERATURE POLYMER ELECTROLYTE MEMBRANE FUEL CELLS ADVENT TECHNOLOGIES HOLDING, INC. (US) 2023-09-28 WO claimed
CN-116444566-A Polynuclear copper nanocluster fluorescent material and preparation method thereof 江苏师范大学 2023-07-18 CN claimed
CN-115745722-A Method for synthesizing diacetylene benzene in one step 珠海固瑞泰复合材料有限公司 2023-03-07 CN claimed
CN-115613390-A Carbon fiber paper and preparation method thereof 泰比达科技(苏州)有限公司 2023-01-17 CN claimed
CN-115322644-A Modified alkynyl polymer coating constructed in situ at interface and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-11-11 CN claimed
CN-113087461-B Insulation board bonding mortar and preparation method thereof 浙江瑞联节能材料有限公司 2022-10-25 CN claimed
CN-109860557-B Lithium ion battery positive electrode material, preparation method thereof and lithium ion battery 河南省鹏辉电源有限公司 2022-08-09 CN claimed
CN-111499401-B High-thermal-conductivity C/SiC composite material and preparation method thereof 湖南东映碳材料科技有限公司 2022-05-10 CN claimed
US-4108942-A FROM A PHENYL ACETYLENE AND DIETHYNYL BENZENE, ALUMINUM-TITANIUM COORDINATION CATALYST GENERAL ELECTRIC COMPANY (US) 1978-08-22 US claimed
US-4100138-A GLASS AND GRAPHITE REINFORCED LAMINATES AND MOLDING COMPOUNDS HUGHES AIRCRAFT COMPANY (US) 1978-07-11 US claimed
US-4098767-A OLIGOMERS, THERMOSETTING, LAMINATES HUGHES AIRCRAFT COMPANY (US) 1978-07-04 US claimed
US-4097460-A DIPHENYLACETYLENE, DIPHENYLBUTADIYNE, MOLDING MATERIALS FOR HIGH TEMPERATURE APPLICATIONS HERCULES INCORPORATED (US) 1978-06-27 US claimed
US-4070333-A AROMATIZATION CATALYST, ADDITION POLYMERIZATION HERCULES INCORPORATED (US) 1978-01-24 US claimed
US-4026860-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US claimed
US-4026859-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US claimed
US-4026861-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US claimed
US-3993711-A THERMOSETTING RESINS; COUPLING AGENTS; CARBOXYLATED PREPOLYMER HERCULES INCORPORATED (US) 1976-11-23 US claimed
US-3931093-A CURING HERCULES INCORPORATED (US) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230302441-A1 WELL DEFINED QUATERNARY AMMONIUM FUNCTIONALIZED QUATERPHENYLENE POLYMER DERIVATIVES FOR LOW AND HIGH TEMPERATURE POLYMER ELECTROLYTE MEMBRANE FUEL CELLS SCNN1B, SCNN1A, HVCN1 HDAC8 1331/4885TSHR 3471/4885LMNA 3304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.