Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889862 | 0.88 | MAPT (0.61) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL4908303 | 0.80 | BCAT2 (0.53) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL3979989 | 0.80 | ALDH1A1 (0.57) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL21771887 | 0.79 | BCAT2 (0.45) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL5176074 | 0.76 | ALDH1A1 (0.52) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL3375243 | 0.75 | MAPT (0.55) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL3977005 | 0.74 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL29795096 | 0.74 | MAPT (0.46) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL11498343 | 0.71 | PTK2 (0.56) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL30511206 | 0.71 | MAPK8 (0.49) | MAPTALDH1A1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7758889-B1 | Fullerenes in targeted therapies | LUNA INNOVATIONS INCORPORATED (US) | 2010-07-20 | — | — | US | disclosed |