Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | NSD2 | O96028 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903143 | 0.87 | HDAC2 (0.73) | HDAC2HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL6253635 | 0.83 | HDAC2 (0.72) | HDAC2HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL12476565 | 0.82 | MAPK1 (0.67) | HDAC2HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL20538849 | 0.81 | KMT2A (0.78) | HDAC7HPGDNSD2KMT2AAPEX1 | |
| SCHEMBL18227526 | 0.80 | ALDH1A1 (0.58) | HDAC1HDAC7HPGDKMT2AAPEX1 | |
| SCHEMBL28146180 | 0.80 | MAPK1 (0.68) | HPGDKMT2AAPEX1CHRNB2CHRNA4 | |
| SCHEMBL28239389 | 0.79 | EGLN1 (0.60) | HPGDNSD2KMT2A | |
| SCHEMBL28042188 | 0.78 | HDAC2 (0.69) | HDAC2HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL6805385 | 0.78 | DEGS1 (0.69) | HDAC8HDAC1PLK1MMP3KMT2A | |
| SCHEMBL28145228 | 0.78 | HTT (0.49) | HPGDNSD2KMT2AAPEX1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516937-A | A kind of synthetic method of sulphoxide imine acylate | 成都理工大学 | 2019-03-26 | — | — | CN | disclosed |