Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764193 | 0.86 | ADRB2 (0.57) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL2267107 | 0.81 | DRD2 (0.50) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL14358826 | 0.81 | DRD2 (0.61) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL7463393 | 0.81 | DRD2 (0.61) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL6588799 | 0.81 | DRD2 (0.61) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL9390026 | 0.81 | DRD2 (0.61) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL7482710 | 0.81 | DRD2 (0.67) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL27497796 | 0.81 | DRD2 (0.51) | DRD2DRD4DRD3MAPK1HTR1A | |
| SCHEMBL5638400 | 0.80 | DRD2 (0.67) | DRD2DRD4DRD3MAPK1KDM4E | |
| SCHEMBL7134153 | 0.78 | DRD2 (0.51) | DRD2DRD4DRD3MAPK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130704-B | It is a kind of to prepare 4- (2- ethoxy) -1,3- dihydro -2H- indol-2-one new method | 上海奥博生物医药技术有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-103130704-B | It is a kind of to prepare 4- (2- ethoxy) -1,3- dihydro -2H- indol-2-one new method | 上海奥博生物医药技术有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-103130704-B | It is a kind of to prepare 4- (2- ethoxy) -1,3- dihydro -2H- indol-2-one new method | 上海奥博生物医药技术有限公司 | 2019-03-22 | — | — | CN | disclosed |