SCHEMBL28870951

SCHEMBL28870951

c1ccc2cc(-c3c4ccccc4cc4cccc(-c5cccc6ccccc56)c34)ccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.51
NQO2 P16083 2/20 0.48
PIM1 P11309 2/20 0.45
ANPEP P15144 1/20 0.44
GPR84 Q9NQS5 2/20 0.43
ALOX5 P09917 1/20 0.42
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 4/20 0.42
HIF1A Q16665 3/20 0.42
HPGD P15428 3/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 2/20 0.42
CASP1 P29466 2/20 0.42
CYP1A2 P05177 2/20 0.42
ERBB2 P04626 1/20 0.42
FYN P06241 1/20 0.42
MAOA P21397 1/20 0.42
ACHE P22303 1/20 0.42
AHR P35869 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041755 1.00 CES1 (0.51) CES1NQO2PIM1ANPEPGPR84
SCHEMBL3043009 0.90 CES1 (0.54) CES1NQO2PIM1ANPEPGPR84
SCHEMBL29775928 0.90 CES1 (0.54) CES1NQO2PIM1ANPEPGPR84
SCHEMBL29034309 0.88 CES1 (0.51) CES1NQO2ANPEPGPR84ALOX5
SCHEMBL28560513 0.85 CES1 (0.56) CES1NQO2ANPEPGPR84ALOX5
SCHEMBL27874728 0.84 CES1 (0.51) CES1NQO2PIM1ANPEPGPR84
SCHEMBL5429989 0.84 CES1 (0.54) CES1NQO2PIM1ANPEPGPR84
SCHEMBL27789679 0.84 ALOX5 (0.49) CES1PIM1GPR84ALOX5ALDH1A1
SCHEMBL27952867 0.83 CES1 (0.61) CES1NQO2ANPEPGPR84ALOX5
SCHEMBL4845570 0.80 CES1 (0.61) CES1NQO2ANPEPGPR84ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651174-A Organic electroluminescent compounds, luminescent material and organic electroluminescence device 苏州久显新材料有限公司 2019-04-19 CN disclosed