SCHEMBL3043009

SCHEMBL3043009

c1ccc2cc(-c3cccc4cc5ccccc5c(-c5ccc6ccccc6c5)c34)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.54
GPR84 Q9NQS5 1/20 0.48
NQO2 P16083 2/20 0.46
HDAC4 P56524 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
GSTP1 P09211 1/20 0.46
ALOX5 P09917 1/20 0.45
CYP1A2 P05177 3/20 0.44
ERBB2 P04626 1/20 0.44
FYN P06241 1/20 0.44
MAOA P21397 1/20 0.44
ACHE P22303 1/20 0.44
AHR P35869 1/20 0.44
ANPEP P15144 1/20 0.43
TSHR P16473 3/20 0.41
HIF1A Q16665 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
MAPK1 P28482 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29775928 1.00 CES1 (0.54) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL29034309 0.94 CES1 (0.51) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL27874728 0.94 CES1 (0.51) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL5429989 0.93 CES1 (0.54) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL30041755 0.90 CES1 (0.51) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL28870951 0.90 CES1 (0.51) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL4845570 0.86 CES1 (0.61) CES1GPR84NQO2ALOX5CYP1A2
SCHEMBL28811230 0.86 CES1 (0.50) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL3978849 0.84 GPR84 (0.46) CES1GPR84NQO2HDAC4HDAC2
SCHEMBL27811186 0.82 GPR84 (0.53) CES1GPR84NQO2HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514139-B1 FLUORINE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME AND METHOD FOR PREPARING SAME LG CHEMICAL LTD (KR) 2024-01-31 EP disclosed
CN-114867703-B Fluorene-based compound, organic light-emitting device using the same, and method for manufacturing the same 株式会社LG化学 2024-01-12 CN disclosed
US-20230098935-A1 Fluorene-Based Compound, Organic Light-Emitting Device Using Same, And Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-03-30 US disclosed
EP-3670610-B1 COATING COMPOSITION, ORGANIC LIGHT-EMITTING DIODE USING SAME, AND METHOD FOR PREPARING SAME LG CHEMICAL LTD (KR) 2023-01-25 EP disclosed
EP-4063342-A1 FLUORENE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR Lg Chem, Ltd. (KR) 2022-09-28 EP disclosed
CN-111094465-B Coating composition, organic light emitting diode using the same, and method of manufacturing the same 株式会社LG化学 2022-08-09 CN disclosed
CN-114867703-A Fluorene-based compound, organic light emitting device using the same, and method of manufacturing the same 株式会社LG化学 2022-08-05 CN disclosed
WO-2021141382-A1 FLUORENE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR 주식회사 엘지화학 2021-07-15 WO disclosed
EP-3670610-A1 COATING COMPOSITION, ORGANIC LIGHT-EMITTING DIODE USING SAME, AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2020-06-24 EP disclosed
US-10680181-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-09 US disclosed
CN-111094465-A Coating composition, organic light emitting diode using the same, and method of manufacturing the same 株式会社LG化学 2020-05-01 CN disclosed
CN-102299165-B Display of organic electroluminescence and manufacture method thereof The special display of the organic thunder of Japan of Co., Ltd. (JP) 2016-01-20 CN disclosed
CN-104039773-A Cyclic azine compound having nitrogen-containing polycyclic aromatic group, method for producing same, and organic electroluminescent element comprising same as constituent component TOSOH CORP 2014-09-10 CN disclosed
US-20140167013-A1 ORGANIC LIGHT EMITTING DIODE DISPLAY AND METHOD FOR FABRICATING THE SAME LG DISPLAY CO., LTD. (KR) 2014-06-19 US disclosed
CN-103872087-A ORGANIC LIGHT EMITTING DIODE DISPLAY AND METHOD FOR FABRICATING THE SAME LG DISPLAY CO LTD 2014-06-18 CN disclosed
CN-101599535-B Light-emitting device, display apparatus, and electronic system SEIKO EPSON CORP 2014-02-12 CN disclosed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP disclosed
US-5935721-A Organic electroluminescent elements for stable electroluminescent EASTMAN KODAK COMPANY (US) 1999-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230098935-A1 Fluorene-Based Compound, Organic Light-Emitting Device Using Same, And Manufacturing Method Therefor AFF1, FAR1, RFT1 CES1 694/4885GPR84 565/4885NQO2 3100/4885
US-10680181-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L CES1 1123/4885GPR84 3941/4885NQO2 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.