Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.64 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871032 | 1.00 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL28871039 | 0.93 | TLR8 (0.54) | TLR8TLR7KCNH2 | |
| SCHEMBL28871041 | 0.93 | TLR8 (0.54) | TLR8TLR7KCNH2 | |
| SCHEMBL28871092 | 0.83 | TLR8 (0.43) | TLR8TLR7KCNH2 | |
| SCHEMBL28871033 | 0.83 | TLR8 (0.43) | TLR8TLR7KCNH2 | |
| SCHEMBL17830000 | 0.81 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL17829980 | 0.81 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL17829986 | 0.81 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL28871034 | 0.80 | TLR8 (0.60) | TLR8TLR7KCNH2 | |
| SCHEMBL18109543 | 0.78 | TLR8 (1.00) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232146-A | 2-aminothieno [2,3-d ] pyrimidine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | disclosed |