Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 14/20 | 0.40 |
| ▸ | CX3CR1 | P49238 | 14/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871092 | 1.00 | TLR8 (0.43) | TLR8TLR7CXCR2CX3CR1ADORA1 | |
| SCHEMBL28871039 | 0.85 | TLR8 (0.54) | TLR8TLR7ADORA1KCNH2 | |
| SCHEMBL28871041 | 0.85 | TLR8 (0.54) | TLR8TLR7ADORA1KCNH2 | |
| SCHEMBL28871032 | 0.83 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL28871035 | 0.83 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL29945147 | 0.79 | CXCR2 (0.39) | TLR8TLR7CXCR2KCNH2 | |
| SCHEMBL28871040 | 0.79 | CX3CR1 (0.40) | TLR8TLR7CXCR2CX3CR1ADORA1 | |
| SCHEMBL18109581 | 0.69 | TLR8 (0.76) | TLR8TLR7CXCR2CX3CR1KCNH2 | |
| SCHEMBL18109579 | 0.69 | TLR8 (0.76) | TLR8TLR7CXCR2CX3CR1KCNH2 | |
| SCHEMBL15469950 | 0.67 | CX3CR1 (0.44) | TLR8TLR7CXCR2CX3CR1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232146-A | 2-aminothieno [2,3-d ] pyrimidine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | disclosed |