Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871039 | 1.00 | TLR8 (0.54) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL28871035 | 0.93 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL28871032 | 0.93 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL28871092 | 0.85 | TLR8 (0.43) | TLR8TLR7KCNH2ADORA1 | |
| SCHEMBL28871033 | 0.85 | TLR8 (0.43) | TLR8TLR7KCNH2ADORA1 | |
| SCHEMBL17829988 | 0.80 | TLR8 (0.60) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL17829978 | 0.80 | TLR8 (0.60) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL28871036 | 0.79 | KCNH2 (0.51) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL28871038 | 0.79 | KCNH2 (0.51) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL29945147 | 0.79 | CXCR2 (0.39) | TLR8TLR7KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232146-A | 2-aminothieno [2,3-d ] pyrimidine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | disclosed |