Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 9/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871515 | 0.87 | PGR (0.52) | PGRBRD4 | |
| SCHEMBL3869130 | 0.80 | PGR (0.72) | PGRNOTUMBRD4 | |
| SCHEMBL28871517 | 0.77 | PGR (0.42) | PGRLPLLIPGBRD4 | |
| SCHEMBL28871523 | 0.75 | PGR (0.43) | PGRBRD4 | |
| SCHEMBL11197568 | 0.75 | PARP1 (0.49) | BRD4 | |
| SCHEMBL10917248 | 0.74 | CA2 (0.50) | PGR | |
| SCHEMBL19805150 | 0.73 | PDE3B (0.42) | PGRGABRA1BRD4 | |
| SCHEMBL10920098 | 0.73 | BRD4 (0.47) | PGRBRD4 | |
| SCHEMBL10915934 | 0.69 | MAOB (0.40) | PGRBRD4 | |
| SCHEMBL23709490 | 0.69 | PGR (0.47) | PGRCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204506-B | CO 2 Synthesis of 1,4-dihydro-2H-3,1-benzoxazine-2-one derivative as C1 source | 常州大学 | 2022-10-28 | — | — | CN | disclosed |